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br Journal of Geriatric Oncology xxx xxx br Contents lists
2020-08-07
Journal of Geriatric Oncology xxx (2019) xxx Contents lists available at ScienceDirect Journal of Geriatric Oncology Barriers and facilitators of adherence to a perioperative physical activity intervention for older adults with cancer and their family caregivers Virginia Sun a, , Dan J
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br Statistical Analysis br After using census tract data to
2020-08-06
Statistical Analysis After using census tract data to estimate the household income for each individual patient, the median household income for the entire study population was calculated. Patients were then catego-rized into low- or high-income groups relative to the median household income fo
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br performance status women also may
2020-08-04
performance status (women also may have a reduced risk of Hexa His tag peptide relapse compared with men, but this association only trended to significance). This finding aligns with a large body of literature showing superior survival in women compared with men in many different cancer types.36-
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br Cell cycle was analyzed using a Cell Cycle
2020-08-04
Cell cycle was analyzed using a Cell Cycle Detection Kit (Keygentec, Nanjing, China). A549 cells were harvested and washed twice with PBS at 24 h after treatments. Cells were then fixed in 1 ml 70% pre-cooled ethanol at 4 ℃ overnight, followed by incubation with 100 mg/l RNaseA at 37℃ for 30 min.
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br ARv Preferentially Interacts with Transcriptional Corepre
2020-08-04
ARv7 Preferentially Interacts with Transcriptional Corepressors Given the codependent binding of ARfl and ARv7 to chromatin, but divergent transcriptional output, we speculated that other factors might contribute to the divergent genomic function of the two receptors. To address this, we first
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br APPBP interacts with microtubules
2020-08-03
APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein (APP) transport and/or processing [3]. Microtubules participate in the formation of the spindle during cell division (mitosis) responsible for cell proliferation. APP is a membrane protein express
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br aPKC mediated ROS inhibition enhances gemcitabine resista
2020-08-03
3.5. aPKCι-mediated ROS inhibition enhances gemcitabine resistance in GBC Next, we further investigated whether aPKCι would influence the sensitivity of GBC MPP+ Iodide to commonly used chemotherapeutic drugs gemcitabine. Given that ROS has been reported to participate in che-moresistance, we
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br D Daddiouaissa et al br the therapeutic
2020-08-02
D. Daddiouaissa, et al. the therapeutic effects of the fruit extract as well as the determination of the active compounds responsible for cytotoxicity. Conflicts of interest There is no conflict of interest in this work. Acknowledgment The authors are grateful to the International Is
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br Gubbels JA Belisle J Onda M
2020-07-31
31. Gubbels JA, Belisle J, Onda M, et al. Mesothelin-MUC16 binding is a high af-finity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors. Mol Cancer 2006; 5:50. r> 32. Thomas A, Chen Y, Steinberg SM, et al. High mesothelin expression in advanced lung adenoc
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br Sensitivity analyses were performed for the
2020-07-29
Sensitivity analyses were performed for the 16 830 men who were treated to 66.6–86.4 Gy and with known information on whether pelvic Dynasore nodes were also treated. In these regression models, information on treatment volume (whole-pelvis, prostate-only), use of dose escalation (no [ Adjusted
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br The data regarding outcomes resulting from symptomatic
2020-07-28
The data regarding outcomes resulting from symptomatic versus nonsymptomatic relapse identification are conflicting. A study evaluating patients enrolled onto the neoadjuvant CRT Intergroup 0160 and 0139 trials demonstrated no survival benefit with more intensive imaging surveillance.15 Additional
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br are thought to cause CC
2020-07-27
are thought to cause CC and they express E6, E7, E1 and E2 oncogenes in the early stages and L1, L2 and E4 in late stages. E6 mediates pro-teasome dependent or independent p53 (a tumor suppressor) turnover and inactivates MDM2 while E7 mediates phosphorylated pRb-medi-ated release of E2F that enha
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br The reduction of ESTAC
2020-07-27
The reduction of 7ESTAC01 showed the first cathodic peak at EIc = −0.38 V, which was lower than the 9-aminoacridine alone. This behaviour hinted a possible synergic activity of 7ESTAC01 due to the significant shift of the first cathodic peak potential. It is worth men-tioning that most of the bioa
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br Cell culture and compounds br LNCaP CRL and PC
2020-07-26
2.2. Cell culture and compounds LNCaP (CRL-1740) and PC-3 (CRL-1435) Erastin were purchased from the American Type Culture Collection (ATCC) and maintained in RPMI 1640 and Ham’s F-12K medium, respectively. DU145 cells were a kind gift of Dr. Robert Bristow (University Health Network) and were
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br Conflicts of interest br The authors
2020-07-08
Conflicts of interest The authors declare no conflict of interest. References Lu, T., Sun, L., Zhu, X., 2018. Yes-associated protein enhances proliferation and attenu-ates sensitivity to cisplatin in human gastric cancer cells. Biomed. Pharmacother. 105, 1269–1275. Pavlova, N.N., Thompso